What question did this study set out to answer?

Evaluate the median survival of patients with MGMT unmethylated glioblastomas treated at a specialized neuro-oncology center.

November 1, 2025Neuro-OncologyOpen Access

NCOG-13. Single institution retrospective analysis of survival of patients with MGMT unmethylated glioblastoma (IDH-wt) at a comprehensive neuro-oncology center

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Authors

APAndrew Pickles VPVikram Prabhu DWDerek Wainwright

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Implication

Retrospective analysis demonstrates median survival of 19 months in glioblastoma patients, suggesting enhanced outcomes in specialized neuro-oncology care.

Key Points

Evaluate the median survival of patients with MGMT unmethylated glioblastomas treated at a specialized neuro-oncology center.
Retrospective analysis of an IRB-approved database from 2020-2024
Included patients with IDH-wt MGMT unmethylated glioblastomas
Assessed treatment with the Stupp protocol
Median survival was 19 months for MGMT unmethylated glioblastomas
28% had multifocal disease with a median survival of 18 months
36% survived at least 24 months; 24% survived at least 36 months, with one patient alive at 72 months

Cite This Study

Pickles et al. (2025) studied this question.

synapsesocial.com/papers/69254362c0ce034ddc358323 https://doi.org/10.1093/neuonc/noaf201.1280

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Implication

Retrospective analysis demonstrates median survival of 19 months in glioblastoma patients, suggesting enhanced outcomes in specialized neuro-oncology care.

NCOG-13. Single institution retrospective analysis of survival of patients with MGMT unmethylated glioblastoma (IDH-wt) at a comprehensive neuro-oncology center

Discussion

Member takes

Implication

Key Points

Cite This Study

NCOG-13. Single institution retrospective analysis of survival of patients with MGMT unmethylated glioblastoma (IDH-wt) at a comprehensive neuro-oncology center

Discussion

Member takes

Implication

Key Points

Cite This Study

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