497 The Impact of Liquid Plasma Implementation on Ordering Patterns Across Departments

Introduction/Objective The introduction of liquid plasma in clinical settings has the potential to alter blood product ordering patterns significantly. This study examines the differences in ordering patterns between thawed plasma and liquid plasma across various departments before and after the implementation of liquid plasma. Methods/Case Report A comparative analysis was conducted on plasma orders from multiple departments, including the emergency department (ED), operating room (OR), pediatrics, intensive care unit (ICU), labor and delivery, oncology, cardiology (CAR), and catheterization lab. Data were collected for two years, focusing on the number of thawed and liquid plasma units ordered. Statistical analyses were performed using chi-square tests to assess the significance of differences in ordering patterns. Results In Year One, no liquid plasma units were ordered across any department, while 315 thawed plasma units were distributed. The ED accounted for 106 units (33.7%), and the OR accounted for 83 units (26.3%). In Year Two, following the implementation of liquid plasma, 121 liquid plasma units were ordered, with the ED ordering 48 units (39.7%) and the OR ordering 33 units (27.3%). The total thawed plasma orders decreased to 641 units, with the ED ordering 150 units (23.4%) and the OR ordering 170 units (26.5%). The analysis revealed a statistically significant difference in the percentage of liquid plasma ordered by the ED compared to thawed plasma (p = 0.005, X² = 20.225). Conclusion The implementation of liquid plasma significantly altered ordering patterns across departments, with a notable increase in liquid plasma orders in the emergency department. The decrease in thawed plasma orders across multiple departments indicates a shift in clinical practice towards utilizing liquid plasma. These findings highlight the importance of monitoring blood product utilization to optimize transfusion practices and improve patient outcomes in trauma care settings.