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November 1, 2025Journal of Food ScienceOpen Access

Bioactive Compounds Extraction From Moringa oleifera Leaves: A Comparative Study of Vacuum‐Assisted and Bed‐Stirred Extractions

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Authors

OGOlívia J.S. GomesALAnabela LeitãoHSHermínio C. de Sousa

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Overview

This study demonstrates improved antioxidant and anti-inflammatory effects of bioactive compounds in Moringa oleifera using vacuum-assisted extraction, suggesting enhanced extraction techniques forbio

Key Points

  • This research aims to compare the extraction efficiency of bioactive compounds from Moringa oleifera leaves using two different methods.
  • Utilized hydroethanolic solvent for both extraction techniques
  • Compared vacuum-assisted extraction (VAE) and bed-stirred extraction (BSE)
  • Applied a design of experiments to optimize solid-solvent ratio and ethanol concentration
  • VAE increased recovery of total phenolic compounds by 37% and flavonoid compounds by 48% compared to BSE
  • VAE extracts showed lower IC 50 values, indicating higher free radical scavenging ability
  • VAE extract exhibited anti-inflammatory activity with IC 50 of 52 ± 1 µg/mL, similar to acetylsalicylic acid

Cite This Study

Gomes et al. (2025) studied this question.

synapsesocial.com/papers/6925437fc0ce034ddc358da9https://doi.org/10.1111/1750-3841.70700
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Also Consider

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