Effect of dexmedetomidine combined with ropivacaine in ultrasound-guided paravertebral nerve block for acute herpes zoster neuralgia patients

Liu Cuicui; Yanting Wang; Pei Wang; Chao Meng; Yanwei Yin

doi:10.4103/ijp.ijp_434_23

October 12, 2025Indian Journal of PharmacologyOpen Access

Effect of dexmedetomidine combined with ropivacaine in ultrasound-guided paravertebral nerve block for acute herpes zoster neuralgia patients

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Key Points

To investigate the efficacy of dexmedetomidine combined with ropivacaine in treating acute herpes zoster neuralgia through nerve block.
Seventy-four patients with acute thoracic herpes zoster neuralgia were prospectively randomized into two groups.
Group I received 0.2% ropivacaine with 1 μg/kg dexmedetomidine; Group II received 0.2% ropivacaine only.
Ultrasound guidance was used for the paravertebral nerve block; pain and sleep quality were assessed via VAS and QS scores.
No significant differences in VAS scores between the groups at any time points (P > 0.05).
QS scores in Group I were significantly lower than Group II at 1, 4, and 8 weeks (P < 0.05).
Pregabalin consumption and PHN incidence showed no significant differences (P > 0.05).
Total times of block in Group I were significantly less than Group II.

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Implication

Shows improved sleep quality in acute herpes zoster patients treated with dexmedetomidine and ropivacaine nerve block, implying benefits for pain management.

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Cuicui et al. (2025) studied this question.

synapsesocial.com/papers/69254f92c0ce034ddc359cbf https://doi.org/10.4103/ijp.ijp_434_23

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Effect of dexmedetomidine combined with ropivacaine in ultrasound-guided paravertebral nerve block for acute herpes zoster neuralgia patients

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Effect of dexmedetomidine combined with ropivacaine in ultrasound-guided paravertebral nerve block for acute herpes zoster neuralgia patients

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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