Simplifying Super-Resolution Microscopy to Accelerate Therapeutic Discovery

Super-resolution microscopy surpasses the limits of ­conventional fluorescence microscopy and enables researchers to visualize and characterize subcellular structures, nanoparticles, and biomarkers with high sensitivity and sub-20-nm resolution. Recent efforts in the field have focused on making super-resolution a precise and quantitative tool, much more accessible to scientists of any skill level. Automation of sample preparation, image acquisition, and analysis with integrated desktop microscopy, and software solutions like those found in the Aplo Platform, are making super-resolution a reliable, user-friendly tool for scientists to assess fundamental disease mechanisms, study drug-cell interactions, and better develop therapies, all with unprecedented detail.