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July 1, 2025Mutation Research/Reviews in Mutation ResearchOpen Access

LRP1B in cancer: From a mutation landscape to predictive biomarkers for precision oncology

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Authors

LYLIKUN YANGXWXi-mo WangXYXiangyang Yu

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Implication

Review examines LRP1B's role in tumorigenesis and immunotherapy in various cancers, suggesting its potential as a therapeutic target.

Key Points

  • The aim is to explore the mutation patterns and clinical significance of LRP1B in cancer.
  • Overview of LRP1B mutation patterns across cancer types
  • Assessment of its role in tumorigenesis and immunological responses
  • Analysis of the implications for personalized medicine in precision oncology.
  • LRP1B mutations affect key processes like genomic stability and antigen presentation.
  • Marked tissue specificity and heterogeneity are seen in LRP1B mutations across cancers.
  • Findings support LRP1B as a promising biomarker and therapeutic target in cancer treatment.

Cite This Study

YANG et al. (2025) studied this question.

synapsesocial.com/papers/69255726c0ce034ddc35a386https://doi.org/10.1016/j.mrrev.2025.108568
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