Research demonstrates analgesic activity in new synthesized N-alkyl-2-arylamino compounds, suggesting potential therapeutic uses.
A series of new N-alkyl-2-arylamino-5,5-dimethyl-4-oxohex-2-enamides were obtained by decyclization of 4-arylamino-2-tert-butyl-2,5-dihydro-5-oxofuran-2-yl acetates under the action of aliphatic amines. The analgesic activity of the synthesized compounds was studied.
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O. V. Zvereva (2025) studied this question.
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