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November 28, 2025United European Gastroenterology JournalOpen Access

Remimazolam Enables Faster Sedation Induction and Recovery Compared With Midazolam in Diagnostic Upper Gastrointestinal Endoscopy: A Multicenter Randomized Controlled Trial

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Authors

YPYehyun ParkJLJun Kyu LeeKLKwang Hyuck Lee

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Overview

Randomized controlled trial showed faster sedation induction and recovery in 132 patients with upper gastrointestinal endoscopy, indicating remimazolam may improve patient satisfaction.

Key Points

  • Faster discharge in the remimazolam group, reducing total procedure time significantly compared to midazolam.
  • Patient satisfaction scores were higher with remimazolam, supporting its use in sedation protocols.
  • Multicenter randomized controlled trial involved 133 participants across seven academic hospitals; results indicate effective sedation management.
  • Remimazolam showed a safety profile similar to midazolam, with lower rates of adverse events like hypotension and bradycardia.

Cite This Study

Park et al. (2025) studied this question.

synapsesocial.com/papers/6928f0f9a65b730b9ea798e5https://doi.org/10.1002/ueg2.70147
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Remimazolam Enables Faster Sedation Induction and Recovery Compared With Midazolam in Diagnostic Upper Gastrointestinal Endoscopy: A Multicenter Randomized Controlled Trial2025
  2. 2Remimazolam vs. midazolam sedation in upper gastrointestinal endoscopy in adults ≥ 65 years: Randomized controlled trial2026 · 2 citations
  3. 3Comparison of Remimazolam and Midazolam for Sedation During Endoscopic Retrograde Cholangiopancreatography‐Related Procedures2026 · 2 citations
  4. 4Response to “Randomized controlled trial of remimazolam compared with placebo in Japanese patients undergoing upper gastrointestinal endoscopy: Phase III investigator‐initiated clinical trial”2024 · 1 citations
  5. 5Efficacy and Safety of Remimazolam versus Midazolam for Sedation during Endoscopic Ultrasound-Guided Tissue Acquisition in Patients with Solid Pancreatic Lesions2026