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This is a Literature Review study.

November 28, 2025Cancer Biology and MedicineOpen Access

Primary cilia in cancer: structures, functions, mechanisms, and therapeutic implications

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Tumor initiation and progression are significantly associated with ciliary dysfunction in certain malignancies, impacting treatment options.
Review emphasizes the role of therapeutic strategies targeting ciliary mechanisms to address malignancies, including cancer.
Analysis of structural and functional abnormalities in primary cilia reveals critical signaling pathways relevant to cancer development.
Understanding primary cilia's role in cellular homeostasis may lead to improved insights and treatments for oncological challenges.

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Implication

Review highlights the link between ciliary dysfunction, tumor initiation, and progression in malignancies, suggesting new therapeutic strategies in oncology.

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Zheng et al. (2025) studied this question.

synapsesocial.com/papers/6928f11ba65b730b9ea7a1bd https://doi.org/10.20892/j.issn.2095-3941.2025.0340

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Implication

Review highlights the link between ciliary dysfunction, tumor initiation, and progression in malignancies, suggesting new therapeutic strategies in oncology.

Primary cilia in cancer: structures, functions, mechanisms, and therapeutic implications

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Discussion

Implication

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Primary cilia in cancer: structures, functions, mechanisms, and therapeutic implications

Key Points

Discussion

Implication

Cite This Study

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