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November 28, 2025Therapeutic Advances in Medical OncologyOpen Access

Genomics of uterine malignancies and the potential of precision medicine

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Authors

JPJoseph PolidanoAJAndrew JarrattCSClare L. Scott

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Overview

Review uncovers molecular profiles and targeted therapies for uterine neoplasms, highlighting precision medicine's promise in treatment.

Key Points

  • Targeted therapies, including HER2-targeted approaches, show promise for uterine malignancies, potentially improving patient outcomes.
  • The review highlights diverse molecular profiles of neoplasms and the need for precision medicine in gynaeoncology.
  • Specific therapies such as trastuzumab deruxtecan and immune checkpoint inhibitors are explored for their transformative potential.
  • Addressing TP53 mutations and utilizing anti-angiogenic strategies may enhance therapeutic strategies for uterine cancers.

Cite This Study

Polidano et al. (2025) studied this question.

synapsesocial.com/papers/6928f126a65b730b9ea7a37ehttps://doi.org/10.1177/17588359251387395
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