Ruthenium-catalyzed allylation improves synthesis of indole derivatives, indicating new pathways for organic synthesis.
The Ru(II)‐ and Rh(III)‐catalyzed CH/CC bond activation and subsequent allylation of 2‐aryl‐3 H ‐indoles with vinylcyclopropanes (VCPs), 2‐vinyl‐ethylene oxide, and 2‐vinylaziridine are reported, enabling the expedient preparation of a wide spectrum for indole derivatives. This transformation proceeds using a cascade sequence involving CH bond activation, CC bond cleavage of VCPs, and 1,2‐migratory alkene insertion.
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Li et al. (2025) studied this question.
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