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November 30, 2025PLoS ONEOpen Access

Sampling informational properties of codon usage through the tree of life

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Authors

OMOctavio MartínezMVManuel Humberto Reyes ValdésNANeftalí Ochoa Alejo

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Overview

Analysis reveals distinct codon usage patterns in Archaea and Bacteria, suggesting complex evolutionary influences on genetic information.

Key Points

  • Codon usage shows significant variability across different taxonomic groups, highlighting evolutionary influences.
  • Conditional entropy measures were used to quantify the relationship between codon components and genetic information.
  • Analysis confirmed that the first codon base significantly influences amino acid determination across 1,434 species.
  • Findings suggest new frameworks for understanding genetic information processing and codon usage adaptations.

Cite This Study

Martínez et al. (2025) studied this question.

synapsesocial.com/papers/692b944c1d383f2b2a378c03https://doi.org/10.1371/journal.pone.0335824
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sampling informational properties of codon usage through the tree of life2025
  2. 2Rules governing the genetic code degeneracy/redundancy and spatial organization of the codon informative properties2024
  3. 3Mapping the Inter- and Intra-genic Codon Usage Landscape in Homo sapiens2025
  4. 4Mapping the inter- and intra-genic codon-usage landscape in <i>Homo sapiens</i>2026
  5. 5Genomic codon usage reveals First-Classness: large-scale empirical validation across the tree of life2025