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This is a Validation Study study.

November 30, 2025MedicineOpen Access

A novel ferroptosis-related microRNAs signature for predicting prognosis in endometrial cancer: An observational study

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Observational study demonstrates a prognostic model predicting endometrial cancer outcomes using five key immune checkpoints and risk scores.

High-risk scores indicated worse overall survival in endometrial cancer patients, highlighting the prognostic significance of the model.
The prognostic model achieved areas under the curve of 0.621, 0.712, and 0.696 for 1, 3, and 5 years, reflecting good predictive ability.
Cox regression analyses were deployed to construct a prognostic model based on risk scores from FermiRNAs.
This model provides independent prognostic evaluation, suggesting new approaches for managing endometrial cancer.

Murakami et al. (2025) studied this question.

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Observational study demonstrates a prognostic model predicting endometrial cancer outcomes using five key immune checkpoints and risk scores.