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November 30, 2025Journal of lasers in medical sciencesOpen Access

Effect of Photobiomodulation Therapy with Three Wavelengths of Diode Laser on Proliferation and Survival of Stem Cells Derived from Impacted Third Molar Follicles

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Authors

MTMona Mohajeri TehraniShariati HospitalFGFatemeh GhahremaniAMAbdolreza Mohamadnia

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Implication

This analysis demonstrates that photobiomodulation significantly boosts cell proliferation in human third molar follicle stem cells, suggesting applications in regenerative dentistry.

Key Points

  • Cell proliferation increased significantly with photobiomodulation at 660 nm and energy density of 5.1 J/cm2.
  • Highest average cell number achieved at 24 hours post-laser exposure, indicating optimal timing and energy density.
  • Statistical analysis used one-way ANOVA and Tukey’s HSD tests with a significance level of 0.05.
  • Implications highlight the potential for standardized photobiomodulation protocols to enhance stem cell therapies.

Cite This Study

Tehrani et al. (2025) studied this question.

synapsesocial.com/papers/692b9d831d383f2b2a379868https://doi.org/10.34172/jlms.2025.49
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The impact of photobiomodulation therapy by diode lasers at wavelengths of 450 nm, 980 nm and their combinations on the proliferation and differentiation of periodontal ligament mesenchymal stem cells2026
  2. 2In vitro effect of simultaneous irradiation of 635 and 980 nm lasers on proliferation of periodontal ligament mesenchymal cells and their differentiation to osteoblasts2026
  3. 3Impact of Photobiomodulation on the Pro-Osteogenic Activity of Dental Pulp Mesenchymal Stem/Stromal Cells2025 · 3 citations
  4. 4In Vitro Photobiomodulation Effects of Blue and Red Diode Lasers on Proliferation and Differentiation of Periodontal Ligament Mesenchymal Stem Cells2024 · 7 citations
  5. 5Influence of Different Photobiomodulation Parameters on Multi-Potent Adipose Tissue Mesenchymal Cells In Vitro2024 · 4 citations