What type of study is this?

This is a Human Clinical Trial study (also classified as: RCT).

November 30, 2025ChildrenOpen Access

Prospective, Non-Blinded, Randomized Controlled Trial of Pulmonary Surfactant Administration Guided by Lung Ultrasound in Preterm Infants with Gestational Age < 32 Weeks

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Randomized controlled trial shows lung ultrasound-guided treatment improves ventilation and reduces radiation exposure in preterm infants with NRDS.

Ultrasound-guided strategy significantly reduced invasive mechanical ventilation rates in preterm infants.
Participants in the ultrasound group received surfactant treatment earlier, needing less overall surfactant.
Non-blinded randomized controlled trial compared ultrasound criteria to conventional clinical guidelines for surfactant administration.
Integrating lung ultrasound may enhance precision in diagnosing NRDS and administering surfactant therapy.

Zhang et al. (2025) studied this question.

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Randomized controlled trial shows lung ultrasound-guided treatment improves ventilation and reduces radiation exposure in preterm infants with NRDS.