November 30, 2025IET Systems BiologyOpen Access

Identification of Ferroptosis‐Related Hub Genes as Diagnosis Biomarkers and Therapeutic Monitoring for Major Depressive Disorder Diagnosis

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Analysis identifies biomarkers for major depressive disorder, suggesting ferroptosis may guide therapeutic strategies.

Ferroptosis may impact the diagnosis of major depressive disorder, enhancing therapeutic strategies and monitoring.
The analysis revealed MAPK14 among biomarkers correlated with immune cell involvement in depression.
Microarray datasets guided the discovery of novel therapeutic targets related to ferroptosis in neuropsychiatric disorders.
These findings may hint at broader implications, emphasizing the need for further exploration in treatment frameworks.

Huang et al. (2025) studied this question.

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