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Nerve Adaptations in the Tumor Microenvironment

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Review outlines how nerve adaptations influence cancer growth and resistance in tumor microenvironments, suggesting novel therapeutic strategies.

Cancer growth is influenced by nerve adaptations, highlighting the role of cancer cells and their interactions.
Nerve regeneration pathways resemble those observed in the structural changes of adjacent nerve terminals.
The mechanisms of therapeutic resistance are intricately linked to the tumor secretome and nerve–tumor interactions.
Nerve adaptations and neuroimmune crosstalk play critical roles in cancer progression, indicating new avenues for treatment.

Swamy et al. (2025) studied this question.

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Review outlines how nerve adaptations influence cancer growth and resistance in tumor microenvironments, suggesting novel therapeutic strategies.