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November 30, 2025Biomedical Chromatography

Screening of ERβ‐Targeted Antipostmenopausal Osteoporosis Chemical Constituents From Cornus officinalis Based on Affinity Ultrafiltration and UHPLC‐Q‐Exactive Orbitrap MS

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Authors

YLYawen LiYLYishan LiKYKunping Yang

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Overview

Analysis identifies active components in traditional Chinese medicine for anti-PMO, suggesting potential for therapy.

Key Points

  • The study confirms that the ERβ enzyme can serve as a target for screening anti-PMO components in traditional Chinese medicine.
  • Analysis used molecular docking to validate interactions between active components and ERβ enzyme.
  • Combination of affinity ultrafiltration and molecular docking offers an effective method for identifying potential therapies.
  • Findings highlight the significance of traditional Chinese medicine in providing novel anti-PMO treatments.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/692b9da91d383f2b2a37a618https://doi.org/10.1002/bmc.70270
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