What type of study is this?

This is a In Vitro Study study.

December 2, 2025Veterinary WorldOpen Access

Optimization of insulin-like growth factor-1 supplementation enhances oocyte quality by modulating oxidative stress and apoptotic pathways during in vitro maturation of Kacang goat oocytes

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Authors

ELEpy Muhammad LuqmanAirlangga University WFWan‐Nor FitriUniversiti Putra Malaysia DKDevia Yoanita KurniawatiAirlangga University

Discussion

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Implication

This analysis reveals that insulin-like growth factor-1 improves oocyte quality by balancing oxidative stress and apoptosis in Kacang goats, suggesting optimal dosages for in vitro maturation.

Key Points

IGF-1 supplementation significantly enhances oocyte quality by regulating oxidative stress indicators and apoptosis markers.
The 100 ng/mL IGF-1 group showed the highest levels of superoxide dismutase and glutathione, crucial for maintaining oocyte quality.
Coupled assessments of oxidative stress and apoptosis were conducted using enzyme-linked immunosorbent assays and immunocytochemistry.
Findings highlight the importance of specific IGF-1 doses for optimizing in vitro maturation of Kacang goat oocytes.

Cite This Study

Luqman et al. (2025) studied this question.

synapsesocial.com/papers/692e3d706c9b3ab28c186eb8 https://doi.org/10.14202/vetworld.2025.3545-3560

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December 2, 2025Veterinary WorldOpen Access

Optimization of insulin-like growth factor-1 supplementation enhances oocyte quality by modulating oxidative stress and apoptotic pathways during in vitro maturation of Kacang goat oocytes

View Full Paper

Ask AI

Bookmark

Authors

ELEpy Muhammad LuqmanAirlangga University WFWan‐Nor FitriUniversiti Putra Malaysia DKDevia Yoanita KurniawatiAirlangga University

Discussion

Member takes

Implication

This analysis reveals that insulin-like growth factor-1 improves oocyte quality by balancing oxidative stress and apoptosis in Kacang goats, suggesting optimal dosages for in vitro maturation.

Key Points

IGF-1 supplementation significantly enhances oocyte quality by regulating oxidative stress indicators and apoptosis markers.
The 100 ng/mL IGF-1 group showed the highest levels of superoxide dismutase and glutathione, crucial for maintaining oocyte quality.
Coupled assessments of oxidative stress and apoptosis were conducted using enzyme-linked immunosorbent assays and immunocytochemistry.
Findings highlight the importance of specific IGF-1 doses for optimizing in vitro maturation of Kacang goat oocytes.

Cite This Study

Luqman et al. (2025) studied this question.

synapsesocial.com/papers/692e3d706c9b3ab28c186eb8 https://doi.org/10.14202/vetworld.2025.3545-3560

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