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October 15, 2025Indian Journal of Animal Research

Insulin-like Growth Factor-1 Supplementation and Early Embryonic Developmental Competence of Immature Cattle Oocytes

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Authors

VSVivek ShahSBS. BeraRMR. Menda

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Overview

Study demonstrates IGF-1 improves embryonic development in oocytes, indicating potential benefits for livestock production.

Key Points

  • IGF-1 at 50 ng/ml significantly enhanced embryo development, particularly cleavage rates.
  • At 50 ng/ml, cleavage rates reached 85.35% at the 2-cell stage and 86.10% at the 4-cell stage.
  • Embryos showed improved morula and blastocyst formation at 50 ng/ml IGF-1 compared to lower concentrations.
  • Statistical analysis utilized one-way ANOVA, confirming the efficacy of IGF-1 supplementation.

Cite This Study

Shah et al. (2025) studied this question.

synapsesocial.com/papers/68eff7392ae617e5891a91e7https://doi.org/10.18805/ijar.b-5671
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Different Growth Factors on in vitro Developmental Competence and Quality of Cattle Oocytes2024
  2. 2Cytokine-Supplemented Maturation Medium Enhances Cytoplasmic and Nuclear Maturation in Bovine Oocytes2024 · 2 citations
  3. 3Optimization of insulin-like growth factor-1 supplementation enhances oocyte quality by modulating oxidative stress and apoptotic pathways during in vitro maturation of Kacang goat oocytes2025
  4. 4FGF2, LIF, and IGF1 supplementation during in vitro maturation or culture improves equine ICSI embryo development in an age-dependent manner2026
  5. 5Insulin Like Growth Factor 1 and Estrogen from Cumulus cell culture increase the success of in vitro fertilization in cattle2025