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December 4, 2025BMC MedicineOpen Access

The effectiveness and safety of a mobile application-based self-regulation intervention to support weight loss among adults living with obesity: a large-scale pragmatic randomised controlled trial

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Authors

SHStella HaffnerSJSusan A. JebbPAPaul Aveyard

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Overview

Randomised controlled trial found mobile app improved weight loss in adults with obesity, suggesting effective self-regulation support.

Key Points

  • Weight loss increased by 1.85 kg in the intervention group compared to control, improving outcomes in participants living with obesity.
  • Mean difference in weight change at six months was −1.85 kg, with two-fold odds of losing ≥5%.
  • Intention-to-treat analyses included all participants, ensuring robust data handling throughout the trial.
  • Mobile application effectively reduced symptoms of disordered eating, indicating strong implications for population health strategies.

Cite This Study

Haffner et al. (2025) studied this question.

synapsesocial.com/papers/6930dc6bea1aef094cca1eaehttps://doi.org/10.1186/s12916-025-04519-8
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Improving weight loss among young adults with excess body weight using a theory-driven digital self-regulation program: a randomized controlled trial2026
  2. 2Design and Pilot Results of a Mobile Phone Weight-Loss Application for Women Starting a Meal Replacement Programme2013 · 71 citations
  3. 3Smartphone App Using Reinforcement Learning for Obesity: Single-Arm Feasibility Study2026
  4. 4The effectiveness of smartphone applications that target eating in facilitating weight loss at six months and longer: A meta-analysis and bias correction2024
  5. 5Meta-analysis of smartphone applications targeting eating behaviour for weight loss2026