Key result
Structured exercise improves peak VO2 by ~1.8 mL/kg/min in mild non-obstructive HCM.
Why the study?
Does structured exercise improve peak oxygen consumption in patients with predominantly low-risk, non-obstructive hypertrophic cardiomyopathy?
Population
290 patients with predominantly low-risk, non-obstructive hypertrophic cardiomyopathy with mild functional…
Comparison
Structured exercise interventions vs Usual care
Design
Meta-analysis
Authors
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Structured exercise safely improves functional capacity and cardiometabolic parameters in patients with mild, non-obstructive hypertrophic cardiomyopathy without increasing adverse events.
Meta-Analysis (n=290)
Does structured exercise improve peak oxygen consumption in patients with predominantly low-risk, non-obstructive hypertrophic cardiomyopathy?
Mean Difference: 1.81 (95% CI 1.01–2.61)
p-value: p=<0.01
Structured exercise safely improves functional capacity and cardiometabolic parameters in patients with mild, non-obstructive hypertrophic cardiomyopathy without increasing adverse events.
Ribeiro et al. (2025) conducted a meta-analysis in Hypertrophic cardiomyopathy (n=290). Structured exercise interventions vs. Usual care was evaluated on peak oxygen consumption (pVO₂) (MD 1.81 mL/kg/min, 95% CI 1.01 to 2.61, p=<0.01). Structured exercise improved peak oxygen consumption (MD 1.81 mL/kg/min; 95% CI 1.01 to 2.61; p<0.01) in patients with mild, non-obstructive hypertrophic cardiomyopathy.
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