Key result
Exercise training in patients with hypertrophic cardiomyopathy provides significant benefits in cardiovascular function and quality of life without increasing the risk of adverse events such as sudden death.
Why the study?
Although guidelines historically recommended restricting exercise in hypertrophic cardiomyopathy due to sudden death concerns, emerging data suggest potential cardiovascular benefits, highlighting a paucity of studies examining exercise effectiveness and safety.
Does exercise training improve cardiovascular function and quality of life without increasing safety risks in individuals with hypertrophic cardiomyopathy?
Does exercise training improve cardiovascular function and quality of life without increasing safety risks in individuals with hypertrophic cardiomyopathy?
Answers are grounded in this paper and cite their sources.
Exercise training in hypertrophic cardiomyopathy provides cardiovascular and quality of life benefits without increasing the risk of sudden death, challenging traditional exercise restriction paradigms.
Background. Hypertrophic cardiomyopathy (HCM) is one of the most common cardiac genetic disorders. The prevalence of this disease is 1 in 500 live births. It is stated to be the most frequent cause of sudden death in young adults. Therefore, some guidelines recommend to restrict physical activity and exercise. On the contrary, latest data show that active lifestyle and exercise in HCM patient provide significant benefits in cardiovascular function with no significant adverse reactions. Following to that, some experts might be reveal that its benefits might be outweigh risks. Summary. There is a paucity of studies that examine the effectiveness of exercise for HCM. American Heart Association (AHA) and (European Society of Cardiology) ESC established exercise recommendations for HCM individuals based on discussion and consensus of experts. We found three studies that investigate the efficacy of exercise in HCM individuals. Outcomes of our interest were differences in cardiovascular function, quality of life and safety issues. All studies found positive significant differences in main outcomes measure in which the HCM subjects on exercise had better or improved outcomes. None reported adverse reaction such as fatal arrhythmia or sudden death related to exercise. Brief Conclusion. Old belief regarding exercise restrictions on HCM need to be reconsidered, given that at present exercise have been shown to provide significant benefits for reducing cardiovascular risk factors. Nevertheless, exercise in patients with HCM must be specifically considered regarding the risk and benefit. Practicing active lifestyle and exercise on HCM individual is an exciting possibility that need further study. Keywords: hypertrophic cardiomyopathy, exercise training, risks and benefit, physical activity
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Deddy Tedjasukmana (2019) conducted a review in Hypertrophic Cardiomyopathy. Exercise training vs. Physical inactivity / usual care was evaluated. Exercise training in patients with hypertrophic cardiomyopathy provides significant benefits in cardiovascular function and quality of life without increasing the risk of adverse events such as sudden death.
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