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December 4, 2025Pharmacognosy MagazineOpen Access

Narirutin Induces Cytotoxicity and Apoptosis in Gastric Cancer Cells Through Oxidative Stress Modulation

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Authors

ZPZhong-Ting PanYGYanling GuoZPZhong-Ting Pan

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Overview

Cytotoxicity and apoptosis induced by narirutin in gastric cancer cells, suggesting it may target oxidative stress pathways.

Key Points

  • Narirutin treatment reduced cell viability and induced apoptosis in gastric cancer cells, enhancing cell death mechanisms.
  • Cell viability was assessed using the MTT assay, revealing significant cytotoxic effects dependent on narirutin concentration.
  • Molecular docking analysis showed narirutin's binding to key apoptotic regulators CASP3 and BAX, supporting its pro-apoptotic effects.
  • These findings highlight narirutin's potential as an anti-cancer agent for gastric cancer through oxidative stress modulation.

Cite This Study

Pan et al. (2025) studied this question.

synapsesocial.com/papers/6930dc92ea1aef094cca2a6dhttps://doi.org/10.1177/09731296251391926
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Also Consider

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