December 4, 2025VirusesOpen Access

Emergence and Pathogenicity of a Novel Goose Adenovirus Type 4 Strain JA2485: Insights for Poultry Disease Control

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Novel goose adenovirus type 4 strain JA2485 shows pathogenic effects, causing 50% mortality in Sanhua geese, highlighting urgent preventive measures.

Pathogenicity tests resulted in 50% mortality in Sanhua geese after infection, indicating serious health risks.
Field isolation and characterization of a novel GoAdV-4 strain (JA2485) expanded knowledge of adenoviruses in waterfowl.
Analysis involved phylogenetic analysis and whole-genome sequencing of the adenovirus strain, revealing close relations with other variants.
The high viral loads found in infected organs suggest potential for fecal transmission, necessitating targeted control strategies.

Gao et al. (2025) studied this question.

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Novel goose adenovirus type 4 strain JA2485 shows pathogenic effects, causing 50% mortality in Sanhua geese, highlighting urgent preventive measures.