December 4, 2025Discover OncologyOpen Access

Extent of bone marrow infiltration predicts disease progression in asymptomatic Waldenström macroglobulinemia

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Authors

NDNicolò DanesinUniversity of Padua GLGiovanni LeoneUniversity of Padua ACAlessandro CelliniUniversity of Padua

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Implication

Observational analysis reveals that higher bone marrow infiltration predicts shorter time to progression in asymptomatic Waldenström Macroglobulinemia, indicating clinical significance.

Key Points

Shorter time to progression is associated with higher bone marrow infiltration levels in asymptomatic Waldenström Macroglobulinemia.
The high BM tumor burden subgroup showed a median time to progression of 64 months versus 137 months for the low burden subgroup.
Multivariate analysis identified elevated serum IgM as an independent predictor of shorter time to progression.
Findings highlight the prognostic significance of bone marrow infiltration in assessing disease progression in Waldenström Macroglobulinemia.

Cite This Study

Danesin et al. (2025) studied this question.

synapsesocial.com/papers/6930dc9eea1aef094cca2e4e https://doi.org/10.1007/s12672-025-04142-2

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Implication

Observational analysis reveals that higher bone marrow infiltration predicts shorter time to progression in asymptomatic Waldenström Macroglobulinemia, indicating clinical significance.

Extent of bone marrow infiltration predicts disease progression in asymptomatic Waldenström macroglobulinemia

Discussion

Member takes

Implication

Key Points

Cite This Study

Extent of bone marrow infiltration predicts disease progression in asymptomatic Waldenström macroglobulinemia

Discussion

Member takes

Implication

Key Points

Cite This Study

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