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December 4, 2025Advanced MaterialsOpen Access

Mitochondria‐Targeted Nanomotor: H 2 S‐Driven Cascade Therapy for Hepatocellular Carcinoma

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Authors

CLChengcheng LiXMXiaodong MaSFShiji Fang

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Implication

Nanomotor therapy improves cancer treatment through metabolic reprogramming in hepatocellular carcinoma, indicating a novel feedback loop and targeting strategy.

Key Points

  • Effective eradication of hepatocellular carcinoma achieved through a feedback loop involving multiple therapies.
  • Photodynamic therapy and metabolic reprogramming enhance therapeutic efficacy against cancer cells.
  • Nanomotors internalize and target mitochondria, boosting photosensitizer delivery and action.
  • Highlights a new paradigm in combination therapies, leveraging mitochondria for improved cancer treatment outcomes.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/6930e8c6ea1aef094cca3470https://doi.org/10.1002/adma.202513757
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