Rh-catalyzed chemodivergent [4+1]-annulation/allylation of sulfoxonium ylides with α-methylene-β-lactones: access to α-indanonyl/α-benzyl acrylates

Swati Samantaray; Sharajit Saha; Tharmalingam Punniyamurthy

doi:10.1039/d5cc05716g

December 2, 2025Chemical Communications

Rh-catalyzed chemodivergent [4+1]-annulation/allylation of sulfoxonium ylides with α-methylene-β-lactones: access to α-indanonyl/α-benzyl acrylates

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Key Points

Sequential C-H functionalization forms α-indanonyl and α-benzyl acrylates with improved yields.
The methodology utilizes sulfoxonium ylides with α-methylene-β-lactones effectively in 4+1-annulation.
Rh-catalyzed reactions demonstrate significant chemodivergence in crafting complex structures.
The findings highlight potential for diverse acrylate synthesis in organic chemistry.

Implication

Rh-catalyzed process produces α-indanonyl and α-benzyl acrylates from sulfoxonium ylides, indicating new synthetic routes.

Abstract

A Rh-catalyzed chemodivergent [4+1]-annulation and allylation of benzoyl sulfoxonium ylides with α-methylene-β-lactones has been achieved to afford α-indanonyl/α-benzyl acrylates. The sequential C-H functionalization and C-C bond formation utilizing the lactones...

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Cite This Study

Samantaray et al. (2025) studied this question.

synapsesocial.com/papers/6930e8cdea1aef094cca38ed https://doi.org/10.1039/d5cc05716g

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Rh-catalyzed chemodivergent [4+1]-annulation/allylation of sulfoxonium ylides with α-methylene-β-lactones: access to α-indanonyl/α-benzyl acrylates

Key Points

Implication

Abstract

Discussion

Cite This Study

Rh-catalyzed chemodivergent [4+1]-annulation/allylation of sulfoxonium ylides with α-methylene-β-lactones: access to α-indanonyl/α-benzyl acrylates

Key Points

Implication

Abstract

Discussion

Cite This Study

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