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December 8, 2025Frontiers in MedicineOpen Access

Multifaceted mechanisms and targeted delivery of mesenchymal stem cell-derived exosomes in cardiovascular diseases: a translational medicine perspective

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Authors

ZLZongjun Liu

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Overview

This review identifies regenerative medicine strategies targeting immune responses in cardiovascular diseases, including myocardial infarction and heart failure, suggesting new therapeutic pathways.

Key Points

  • Cardiovascular diseases remain a leading cause of death globally, necessitating innovative therapies.
  • Key therapeutic mechanisms of MSC-Exo include promoting angiogenesis and inhibiting apoptosis in heart failure and myocardial infarction.
  • Review of preclinical studies reveals MSC-Exo's impact on fibrosis and inflammatory responses, emphasizing its multifunctional role.
  • Innovative delivery methods enhance the efficacy of MSC-Exo, indicating strong potential for clinical translation in regenerative medicine.

Cite This Study

Zongjun Liu (2025) studied this question.

synapsesocial.com/papers/693624a44fa91c937236c269https://doi.org/10.3389/fmed.2025.1729698
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