December 8, 2025Scientific ReportsOpen Access

Association between anosognosia and neuropsychiatric symptoms in Alzheimer’s disease dementia patients

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Discussion

Observational analysis revealed faster onset of apathy in patients with anosognosia, suggesting targeted therapeutic strategies may improve outcomes.

Patients with anosognosia experienced a faster onset of apathy compared to those without it.
Among the 112 patients, 47.3% had anosognosia, indicating symptom prevalence's significance.
Analysis utilized Cox proportional hazards models to assess NPS onset between groups while adjusting for demographic factors.
These findings highlight the need for tailored treatment strategies to manage NPS in Alzheimer's disease patients with anosognosia.

Fawzy et al. (2025) studied this question.

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Observational analysis revealed faster onset of apathy in patients with anosognosia, suggesting targeted therapeutic strategies may improve outcomes.