Synthesis of S-or N-glycomimetics of D-galactono-1,4-lactone. Inhibitors of a β-galactofuranosidase.

In the search for β-galactofuranosidase inhibitors, the synthesis of the 4-thio-D-galactonic acid 1,4-thiolactone and 4-deoxy-D-galactono-1,4-lactam was undertaken. These compounds are analogs of D-galactono-1,4-lactone, a known inhibitor of the enzyme. Additionally,...