What type of study is this?

This is a Cohort Study study (also classified as: Human Clinical Trial).

What question did this study set out to answer?

To evaluate the effect of a new ferritin threshold on diagnosing iron deficiency and treatment patterns.

December 8, 2025BloodOpen Access

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Retrospective cohort study shows increased diagnosis of iron deficiency in women, indicating impact of updated ferritin levels.

To evaluate the effect of a new ferritin threshold on diagnosing iron deficiency and treatment patterns.
Retrospective cohort study using EHR data from Rochester Regional Health
Analysis of patient data before and after updating ferritin lower limits of normal
Primary outcome focused on rates of IDWA and IDA diagnosis
Evaluation of secondary outcomes such as iron prescriptions and hematology referrals
IDWA/IDA diagnosis rate increased from 51.0% to 58.5% after the intervention
Ferritin tests flagged as low rose from 13% to 32% following LLN change
Increased rates of oral (15%) and IV iron prescriptions (17%)
Hematology referrals for IDWA or IDA rose by 14%

Peter A. Kouides (2025) studied this question.

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