Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 8, 2025BloodOpen Access

Iron infusions in pregnant women are associated with comparable efficacy and safety compared to non-pregnant women

View Full Paper
Ask AI
Bookmark
Share

Authors

SFSteven FeinDADayne AlonsoALAdam K. Lewkowitz

Discussion

Loading...

Member takes

Overview

Case series shows comparable safety and efficacy of iron infusions in pregnant and non-pregnant women with iron deficiency, highlighting symptom relief and infusion tolerability.

Key Points

  • This study compares the efficacy, safety, and tolerability of iron infusions in pregnant women with iron deficiency anemia against non-pregnant women with the same condition.
  • Single center case series involving pregnant women in their 2nd or 3rd trimesters receiving iron infusions.
  • Patients were assessed for symptoms of iron deficiency, followed by iron infusions in an outpatient setting.
  • Comparison made with a selected cohort of non-pregnant women who also received iron infusions.
  • Average hemoglobin increase was 1.2g/dL in pregnant women and 1.8g/dL in non-pregnant women.
  • Symptom relief was reported in 82% of pregnant women and 80% of non-pregnant women.
  • Infusion reactions occurred in 3.3% of pregnant women and 3.5% of non-pregnant women.

Cite This Study

Fein et al. (2025) studied this question.

synapsesocial.com/papers/69362f3d4fa91c937236d4d6https://doi.org/10.1182/blood-2025-4477
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effectiveness and Safety of Intravenous Iron Therapy in Outpatient Obstetrical Clinic for Treatment of Iron‐Deficiency Anemia During Pregnancy2025 · 1 citations
  2. 2Treatment optimization for iron deficiency anemia in pregnant women as a resource to prevent perinatal complications2024 · 1 citations
  3. 3Single-dose IV ferric derisomaltose improves hematologic and patient-reported outcomes in pregnant individuals with iron deficiency anemia2025
  4. 4Intravenous vs Oral Iron for Treating Iron Deficiency Anemia in Pregnancy2026
  5. 5Intravenous Iron Supplementation in Pregnancy: Comparisons of Dosage and Latency of Infusion Based on a Quality Improvement Project on Maternal Transfusion Reduction [ID 2683380]2024