What question did this study set out to answer?

This research evaluates the healthcare costs associated with allogeneic stem cell transplantation for sickle cell disease.

December 8, 2025BloodOpen Access

Analysis of healthcare utilization costs prior to and after non-myeloablative haploidentical allogeneic stem cell transplantation in adults with sickle cell disease

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Authors

IAIjele AdimoraJohns Hopkins University RBRobert A. BrodskyJohns Hopkins University JBJeromie BallreichJohns Hopkins University

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Implication

Analysis shows reduced healthcare utilization costs in sickle cell disease after allogeneic stem cell transplantation, indicating potential cost effectiveness.

Key Points

This research evaluates the healthcare costs associated with allogeneic stem cell transplantation for sickle cell disease.
Performed a single-center evaluation of healthcare utilization costs
Analyzed billing records for 22 adult patients
Measured costs 30 days pre- and 90 days post-transplant
Identified key utilization metrics using CPT codes and revenue codes
Median pre-transplant charges were $136,079 per patient
Post-transplant charges reduced to a median of $70,000
Inpatient admissions decreased from 1.26 to 0.50 per 100 exposure days
Emergency room visits decreased from 0.78 to 0.52 per 100 exposure days
Vaso-occlusive crises reduced from 1.85 to 0.58 per 100 exposure days

Cite This Study

Adimora et al. (2025) studied this question.

synapsesocial.com/papers/69362f444fa91c937236d5a9 https://doi.org/10.1182/blood-2025-2599

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Implication

Analysis shows reduced healthcare utilization costs in sickle cell disease after allogeneic stem cell transplantation, indicating potential cost effectiveness.

Analysis of healthcare utilization costs prior to and after non-myeloablative haploidentical allogeneic stem cell transplantation in adults with sickle cell disease

Discussion

Member takes

Implication

Key Points

Cite This Study

Analysis of healthcare utilization costs prior to and after non-myeloablative haploidentical allogeneic stem cell transplantation in adults with sickle cell disease

Discussion

Member takes

Implication

Key Points

Cite This Study

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