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December 8, 2025Blood

Clinical characteristics and outcomes of extranodal marginal zone lymphoma of pulmonary mucosa-associated lymphoid tissue: A single-center retrospective study

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Authors

CZChunxia ZhangPutian UniversityCGChao GuoChinese Academy of Medical Sciences & Peking Union Medical CollegeYHYuan HuangCentral South University of Forestry and Technology

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Overview

Retrospective study reveals clinical characteristics and treatment outcomes in patients with pulmonary malt lymphoma, suggesting a need for better treatments.

Key Points

  • This research aims to summarize the clinical characteristics and treatment outcomes of patients with pulmonary MALT lymphoma.
  • Collected retrospective data from patients diagnosed with pulmonary MALT lymphoma since January 2010
  • Included demographic characteristics, laboratory tests, imaging results, comorbidities, and treatment plans
  • Conducted various diagnostic methods including CT-guided lung biopsy and bronchoscopy
  • Included 41 patients with a median age of 64 years
  • Reported a median lactate dehydrogenase level of 172.5 U/L
  • 56.1% of patients had Ann Arbor stage IV disease
  • 14 patients received R-CHOP-like regimens as first-line treatment with an objective response rate of 85.7%

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/69362f484fa91c937236d719https://doi.org/10.1182/blood-2025-7132
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pulmonary mucosa-associated lymphoid tissue lymphoma: insights from a 15-year study at a single institution involving 14 clinical cases2024 · 5 citations
  2. 2Comparisons of Surgery and/or Chemotherapy in the Treatment of Primary Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma2014 · 11 citations
  3. 3Clinical characteristics, diagnosis, treatment, and prognostic factors of pulmonary mucosa‐associated lymphoid tissue‐derived lymphoma2019 · 43 citations
  4. 4A80-4-26 When Opacities Hide a Lymphoma: A Rare Case of Diffuse Pulmonary MALT Lymphoma2026
  5. 5C79-28 The One That Got Away: The Elusive Diagnosis of Pulmonary Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma2026