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December 8, 2025BloodOpen Access

Treatment practices and outcomes of advanced stage classical Hodgkin lymphoma in India: An analysis from the hematology cancer consortium

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Authors

DBDinesh BhuraniSDSanthosh Kumar DevadasSVSreeraj Vasudevan

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Overview

Retrospective analysis reveals ABVD efficacy and key prognostic factors for event-free survival in advanced cHL patients.

Key Points

  • This study evaluates treatment practices and outcomes for advanced stage classical Hodgkin lymphoma in India.
  • Retrospective cohort study across 10 centers in India
  • Analyzed treatment data from 1524 patients, 876 with advanced stage cHL
  • Utilized interim response assessment via FDG-PET/CT and other imaging techniques
  • ABVD was used in 89% of patients, achieving a 2-year event-free survival of 79%
  • Low albumin and hemoglobin were associated with inferior event-free survival
  • iPET response strongly predicted event-free survival, outperforming the International Prognostic Score

Cite This Study

Bhurani et al. (2025) studied this question.

synapsesocial.com/papers/69362f484fa91c937236d71dhttps://doi.org/10.1182/blood-2025-7133
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Treatment of Patients with Local Stages of Newly Diagnosed Classical Hodgkin Lymphoma: A Literature Review, Current Approaches, and Our Own Experience2024
  2. 2Long-term clinical outcomes of combined modality therapy for advanced-stage Hodgkin lymphoma in the PET era: A retrospective study2024 · 1 citations
  3. 3Real world outcome of nodal T cell non-Hodgkin lymphoma from hematology cancer consortium registry in India2025
  4. 4CLINICAL FEATURES AND THERAPEUTIC OUTCOMES OF CLASSICAL HODGKIN LYMPHOMA: A RETROSPECTIVE REVIEW FROM TERTIARY CENTER IN SOUTHERN INDIA2026
  5. 5Interim PET‐guided ABVD or ABVD/escalated BEACOPP for newly diagnosed advanced‐stage classic Hodgkin lymphoma (JCOG1305)2024 · 4 citations