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December 8, 2025BloodOpen Access

Real world outcome of nodal T cell non-Hodgkin lymphoma from hematology cancer consortium registry in India

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Authors

LNLingaraj NayakMAMithun AbrahamPKParathan Karunakaran

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Overview

Registry analysis reports poor outcomes in nodal T-NHL with diverse chemotherapy protocols and high toxicity rates.

Key Points

  • This research aims to evaluate real-world outcomes of nodal T cell non-Hodgkin lymphoma based on a registry in India.
  • Data from a prospective lymphoma registry were analyzed for characteristics and outcomes.
  • 294 patients aged ≥18 from 10 centers were included from January 2020 to May 2023.
  • Treatment regimens varied by center, focusing on chemotherapy types and stem cell transplant outcomes.
  • 68% achieved complete response to first-line therapy; 14% had partial response, 14% experienced progressive disease.
  • 42% of patients were lost to follow-up, impacting overall outcomes.
  • The median event-free survival was 29 months, with poor outcomes noted across most prognostic factors.

Cite This Study

Nayak et al. (2025) studied this question.

synapsesocial.com/papers/69362f484fa91c937236d738https://doi.org/10.1182/blood-2025-7154
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  5. 5Treatment practices and outcomes of advanced stage classical Hodgkin lymphoma in India: An analysis from the hematology cancer consortium2025