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December 8, 2025BloodOpen Access

Comparable outcomes after autologous hematopoietic cell transplantation in T-cell lymphoma regardless of pre-transplant response: A key finding in resource-limited countries.

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Authors

SGSebastián GaleanoRGRosanna De GiudaCOCristina Otero

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Overview

Retrospective analysis reveals improved progression-free survival in T-cell lymphoma after autologous hematopoietic cell transplantation.

Key Points

  • To assess outcomes of autologous hematopoietic cell transplantation in patients with T-cell lymphoma.
  • Retrospective, multi-institutional study of adults in Uruguay
  • Included patients diagnosed with T-cell lymphoma who underwent autologous hematopoietic cell transplantation
  • Analyzed data on progression-free survival and overall survival
  • Five-year progression-free survival was 59% and overall survival was 62%
  • Patients achieving complete response after transplantation had a median duration of response of 104 months
  • Survival rates varied by subtype, with anaplastic T-cell lymphoma patients showing the highest five-year overall survival at 79%

Cite This Study

Galeano et al. (2025) studied this question.

synapsesocial.com/papers/69362f574fa91c937236da55https://doi.org/10.1182/blood-2025-2777
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hematopoietic stem cell transplantation in T-cell lymphomas: A promising strategy challenging poor prognosis2025
  2. 2Real world outcome of nodal T cell non-Hodgkin lymphoma from hematology cancer consortium registry in India2025
  3. 3A Deeper Depth of Response After Salvage Therapy Improves Outcomes of Autologous Stem Cell Transplantation in Relapsed Lymphoma and the Feasibility of Non-controlled Rate Freezing of Peripheral Blood Stem Cells2024
  4. 4The role of hematopoietic stem cell transplantation in peripheral T-cell lymphoma not otherwise specified2025
  5. 5Survival outcomes after autologous stem cell transplantation in T follicular helper type lymphoma.2024