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December 8, 2025BloodOpen Access

Evaluating the management of severe anemia in the emergency department: A single-center analysis

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Authors

KAKabeer Ali

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Overview

Retrospective analysis reveals high transfusion rates in emergency departments for severe anemia, while diagnostics often neglect iron and vitamin deficiencies, suggesting a need for improved care.

Key Points

  • To evaluate the management and diagnostics of severe anemia in emergency departments, with emphasis on transfusion practices and deficiencies.
  • Conducted a retrospective chart review in a single center
  • Included adult patients with hemoglobin ≤9 g/dL who received RBCs
  • Assessed diagnostic tests for iron, vitamin B12, and folate levels
  • Out of 270 screened, 45 patients met inclusion criteria
  • Iron deficiency present in 82% of patients, with 16% receiving IV iron
  • Majority of patients had microcytic anemia, and vitamin B12 testing was incomplete for 36%

Cite This Study

Kabeer Ali (2025) studied this question.

synapsesocial.com/papers/69362f4b4fa91c937236d7bdhttps://doi.org/10.1182/blood-2025-2616
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidence and diagnosis of iron deficiency among patients receiving a blood transfusion in the emergency department2025
  2. 2First‐time red blood cell transfusions in the emergency department: A deficiency in micronutrient testing2026
  3. 3Utilization of Intravenous Iron Therapy and Red Blood Cell Transfusion in Emergency Department Patients with Anemia: A Single-Center Retrospective Cohort Study2026
  4. 4In-hospital stay of anemic patients (70-90 g.L-1) in the ED with/without transfusion: a single-center propensity-matched study.2024
  5. 5Assessing clinical practice variation and provider comfort in the management of pediatric iron deficiency anemia in the acute care setting2025