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December 8, 2025BloodOpen Access

Availability of blood products and transfusion practices in sub-saharan Africa for the management of patients with sickle cell disease: A survey in 16 countries.

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Authors

FBFrançoise BernaudinFGFrédéric GalactérosMMMariane de Montalembert

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Overview

Online survey assessed transfusion practices in sickle cell disease across 16 countries, suggesting improvements in blood product availability and management of acute complications.

Key Points

  • To assess blood product availability and transfusion practices in patients with sickle cell disease in sub-Saharan Africa.
  • Conducted an online survey involving 1,960 physicians in 16 French-speaking SSA countries.
  • Utilized a standardized questionnaire developed by DrepAfrique's scientific council.
  • Collected data on practices related to red blood cell transfusions and hemoglobin management.
  • Only 26.4% of practitioners performed phlebotomy prior to transfusion in patients with hemoglobin >9 g/dL.
  • Transfusions were most often used during vaso-occlusive crises and in cases of severe anemia.
  • Only a small percentage (40.3%) used transfusions in stroke cases, indicating a need for better protocols.

Cite This Study

Bernaudin et al. (2025) studied this question.

synapsesocial.com/papers/69362f514fa91c937236d99bhttps://doi.org/10.1182/blood-2025-2966
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A global survey of blood transfusion practices for patients with sickle cell disease2026
  2. 2Full assessment of clinical transfusion support (FACTS): A prospective Study to determine the burden of sickle cell anemia on pediatric blood transfusion use in a malaria-endemic region in Africa2025
  3. 3Transfusion safety in francophone African countries: an analysis of strategies for the medical selection of blood donors2011 · 46 citations
  4. 4Red blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviews2026
  5. 5Transforming Hematology Care in Africa: Strategies for Enhanced Diagnosis and Treatment2026 · 1 citations