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Evaluate evolution of treatment patterns and clinical outcomes in multiple myeloma patients from 2012 to 2023.

December 8, 2025BloodOpen Access

Updated analysis of survival and treatment evolution in european multiple myeloma patients (2012–2023) across 7 countries from the honeur network

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Updated analysis reveals improved clinical outcomes in European multiple myeloma patients undergoing stem cell transplant.

Evaluate evolution of treatment patterns and clinical outcomes in multiple myeloma patients from 2012 to 2023.
Analyzed data from 10 European multiple myeloma registries
Included patient-level data from over 30,000 multiple myeloma patients
Assessed time to next treatment and overall survival using Kaplan-Meier and proportional hazards regression
Conducted subanalysis on patients receiving stem cell transplant
Median frontline time to next treatment improved from 28.9 months to 32.4 months
Overall survival increased from 74.1 months to not reached during the study period
SCT significantly improved patient outcomes with median overall survival of 138.4 months for transplanted patients

Jungová et al. (2025) studied this question.

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