Propensity score-matched analysis supports the survival benefits of combination chimeric antigen receptor T-cell therapy with autologous transplantation in relapsed or refractory B-cell non-Hodgkin lymphoma: Insights from a real-world study in China
Observational study shows improved overall and progression-free survival with CAR-T and autologous transplantation in B-cell lymphoma patients, indicating enhanced treatment effectiveness.
Key Points
This study evaluates the survival benefits of combining autologous transplantation with CAR-T therapy in B-cell non-Hodgkin lymphoma.
Retrospective analysis of 217 patients with NHL hospitalized in China
Compared ASCT combined with CAR-T therapy versus CAR-T monotherapy
Used propensity score matching to reduce confounding variables
Applied multivariable Cox regression for statistical analysis.