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December 8, 2025BloodOpen Access

Presenting features, treatment patterns and predictors of outcomes in AL amyloidosis at a tertirary care cancer centre

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Authors

AAArpit AroraPTPrashant TembhareNPNikhil Patkar

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Overview

Retrospective analysis highlights renal involvement and treatment responses as key predictors of outcomes in AL amyloidosis.

Key Points

  • To analyze the presentation and treatment outcomes of patients with AL amyloidosis and identify predictors of outcomes.
  • Conducted a retrospective observational study of patients diagnosed with AL amyloidosis.
  • Data obtained from electronic medical records regarding demographics, clinical features, and treatment regimens.
  • Analyzed outcomes using SPSS 31.0.
  • Included a total of 93 patients with a median age of 60 years.
  • Main organ involvement: Kidney (71%), Heart (63.4%), with 63.4% having multiple organs affected.
  • 24-month progression-free survival was 58% and overall survival rates were 72% at 24 months. Early mortality occurred in 41.6% of deaths.

Cite This Study

Arora et al. (2025) studied this question.

synapsesocial.com/papers/69362f6e4fa91c937236e08chttps://doi.org/10.1182/blood-2025-7501
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