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December 8, 2025Blood

A national analysis on ALK+ anaplastic large cell lymphomas: Community-based care linked to similar survival outcomes compared to academic centers.

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Authors

EKErin KaserSKSupreet Kaur

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Overview

Retrospective analysis reports similar survival outcomes in patients with ALK+ anaplastic large cell lymphomas at community and academic cancer programs.

Key Points

  • This analysis aims to compare survival outcomes for patients with ALK+ anaplastic large cell lymphomas treated at academic versus community cancer programs.
  • Retrospective analysis of ALK+ ALCL patients in the United States from 2004 to 2022 using the National Cancer Database.
  • Comparison of demographic, clinical, and survival data between academic cancer programs and community cancer programs.
  • Survival outcomes assessed using Kaplan-Meier and Cox proportional hazards models.
  • 9,197 patients with ALK+ ALCL were identified, with 45% treated at academic centers and 33% at community centers.
  • Patients at academic centers had more advanced-stage disease but no significant difference in overall survival compared to community programs.
  • Median adjusted survival time was 4.78 years for academic centers and 4.99 years for community centers.

Cite This Study

Kaser et al. (2025) studied this question.

synapsesocial.com/papers/69362f714fa91c937236e1abhttps://doi.org/10.1182/blood-2025-3642
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Also Consider

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  5. 5Improved survival outcomes in angioimmunoblastic T-cell lymphoma linked to care at academic cancer centers: A national cancer database study.2025