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December 8, 2025BloodOpen Access

Impact of iron deficiency anemia on outcomes in postpartum hemorrhage: Insights from a national inpatient sample analysis

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Authors

SRSruthi Ramanan SASowbharnika Arivazhagan HJHardik Jain

Discussion

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Overview

Analysis reveals iron deficiency anemia impacts length of stay and costs in postpartum hemorrhage cases, indicating critical maternal health concerns.

Key Points

To assess the impact of iron deficiency anemia on outcomes in postpartum hemorrhage using national hospitalization data.
Utilized the 2021 National Inpatient Sample to identify hospitalizations for postpartum hemorrhage using ICD-10 code 'O72'.
Identified iron deficiency anemia using ICD-10 prefix 'D50'.
Employed survey-weighted logistic and linear regression models to evaluate associations between iron deficiency anemia and outcomes.
Adjusted models for age, race, Charlson comorbidity index, hospital region, teaching status, bed size, and income quartile.
Among 182,080 hospitalizations for postpartum hemorrhage, 4.8% had concurrent iron deficiency anemia.
Patients with iron deficiency anemia were, on average, younger and more likely to be Black or Hispanic.
Iron deficiency anemia was not associated with increased inpatient mortality.
Iron deficiency anemia was independently associated with longer hospital stays and increased healthcare costs.

Cite This Study

Ramanan et al. (2025) studied this question.

synapsesocial.com/papers/69362f7d4fa91c937236e434 https://doi.org/10.1182/blood-2025-6171

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December 8, 2025BloodOpen Access

Impact of iron deficiency anemia on outcomes in postpartum hemorrhage: Insights from a national inpatient sample analysis

View Full Paper

Ask AI

Bookmark

Authors

SRSruthi Ramanan SASowbharnika Arivazhagan HJHardik Jain

Discussion

Member takes

Overview

Analysis reveals iron deficiency anemia impacts length of stay and costs in postpartum hemorrhage cases, indicating critical maternal health concerns.

Key Points

To assess the impact of iron deficiency anemia on outcomes in postpartum hemorrhage using national hospitalization data.
Utilized the 2021 National Inpatient Sample to identify hospitalizations for postpartum hemorrhage using ICD-10 code 'O72'.
Identified iron deficiency anemia using ICD-10 prefix 'D50'.
Employed survey-weighted logistic and linear regression models to evaluate associations between iron deficiency anemia and outcomes.
Adjusted models for age, race, Charlson comorbidity index, hospital region, teaching status, bed size, and income quartile.
Among 182,080 hospitalizations for postpartum hemorrhage, 4.8% had concurrent iron deficiency anemia.
Patients with iron deficiency anemia were, on average, younger and more likely to be Black or Hispanic.
Iron deficiency anemia was not associated with increased inpatient mortality.
Iron deficiency anemia was independently associated with longer hospital stays and increased healthcare costs.

Cite This Study

Ramanan et al. (2025) studied this question.

synapsesocial.com/papers/69362f7d4fa91c937236e434 https://doi.org/10.1182/blood-2025-6171

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