Splenic dysfunction in young children with sickle cell disease

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Comparative histological analysis of spleens in pediatric patients with hemolytic anemias: Insights into the pathophysiological mechanisms of spleen destruction in sickle cell anemia2024 · 5 citations
2. 2Downregulation of cytokine responses and STAT signaling in children with sickle cell disease2026
3. 3Clearance of pathogenic erythrocytes is maintained despite spleen dysfunction in children with sickle cell disease2024 · 7 citations
4. 4Evaluation of Splenic Morphology and Its Relationship with Clinical Manifestations and Hematological Parameters in Indian Patients with Homozygous Sickle-cell Disease2026
5. 5Single-cell analysis reveals distinct γ-globin expression profiles in sickle cell disease with pancellular fetal hemoglobin2025