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December 8, 2025BloodOpen Access

Trends in death from multiple myeloma with concomitant diabetes mellitus in the USA

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Authors

GGGunwant Guron

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Overview

Analysis shows rising mortality in multiple myeloma with diabetes, highlighting regional, gender, and racial disparities.

Key Points

  • To assess temporal trends in mortality from multiple myeloma associated with diabetes in the USA.
  • Analyzed DM-related MM mortality data from 1999 to 2020 using CDC WONDER.
  • Calculated age-adjusted mortality rate (AAMR) per 100,000 individuals.
  • Applied joinpoint trend analysis to assess average annual percent change (AAPC) in AAMR.
  • Total of 12,296 deaths attributed to MM with concomitant DM from 1999 to 2020.
  • Overall AAMR increased from 0.41 to 0.49 per 100,000 individuals during the study period.
  • Men had higher AAMR (0.64) than women (0.34) for DM-associated MM.

Cite This Study

Gunwant Guron (2025) studied this question.

synapsesocial.com/papers/69362f7d4fa91c937236e4e8https://doi.org/10.1182/blood-2025-7528
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Trends in mortality from multiple myeloma and diabetes mellitus in the United States: A retrospective analysis from 1999 to 20202025
  2. 2Trends in Acute Myeloid Leukemia mortality among patients with diabetes mellitus in the United States, 1999–2024: A CDC wonder database analysis2025
  3. 3Multiple myeloma incidence and mortality trends in the United States, 1999–20202024 · 33 citations
  4. 4Multiple myeloma incidence and mortality trends in the United States, 1999-20202024 · 3 citations
  5. 5Trends in renal failure–related mortality among U.S. multiple myeloma patients aged ≥ 45 years, 1999–2023: analysis of CDC data2026