What question did this study set out to answer?

To evaluate the prognostic value of nutritional indices including serum albumin and GNRI in patients after first allogeneic stem cell transplantation.

December 8, 2025BloodOpen Access

Serum albumin, but not gnri, is an independent prognostic factor for survival after first allogeneic SCT: A large-scale multicenter analysis

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To evaluate the prognostic value of nutritional indices including serum albumin and GNRI in patients after first allogeneic stem cell transplantation.
Retrospective analysis of 3,178 SCT1 patients with various hematopoietic malignancies from KSGCT database.
Evaluated 5-year overall survival, non-relapse mortality, and cumulative incidence of relapse.
Conducted ROC curve analyses to assess the predictive accuracy of nutritional indicators.
5-year overall survival was 51.1% with significant differences in survival based on nutritional markers.
Serum albumin showed better predictive accuracy than GNRI and BMI, with significant p-values.
Developed a scoring system based on independent predictors including serum albumin, age, and CRP levels.

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Implication

Analysis demonstrates serum albumin is a vital prognostic factor for survival in allogeneic SCT, suggesting improved risk assessment strategies.

Cite This Study

Fujiwara et al. (2025) studied this question.

synapsesocial.com/papers/69362f7f4fa91c937236e539 https://doi.org/10.1182/blood-2025-2513

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Implication

Analysis demonstrates serum albumin is a vital prognostic factor for survival in allogeneic SCT, suggesting improved risk assessment strategies.

Serum albumin, but not gnri, is an independent prognostic factor for survival after first allogeneic SCT: A large-scale multicenter analysis

Key Points

Discussion

Implication

Cite This Study

Serum albumin, but not gnri, is an independent prognostic factor for survival after first allogeneic SCT: A large-scale multicenter analysis

Key Points

Discussion

Implication

Cite This Study

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