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December 11, 2025SLEEP

Objective sleepiness without a subjective complaint decreases hypertension risk

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Authors

NANikolaos AthanasiouSPSlobodanka PejovicJFJulio Fernández‐Mendoza

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Overview

Cross-sectional analysis reveals objective sleepiness reduces hypertension risk in adults, suggesting new screening approaches.

Key Points

  • To explore the association of objective sleepiness without excessive daytime sleepiness with hypertension risk.
  • Cross-sectional analysis of 1590 adults without a complaint of EDS from the Penn State Cohort.
  • Longitudinal follow-up of 659 subjects without hypertension over an average of 7.5 years.
  • Objective sleepiness defined as sleep onset latency ≤ 7 minutes during polysomnography, with hypertension determined by blood pressure or medication use.
  • Binary logistic regression was conducted while controlling for covariates.
  • Objective sleepiness group had significantly lower prevalence of hypertension (22.1% vs. 32.3%).
  • Incident hypertension was also lower in this group (8.8% vs. 17.3%).
  • Objective sleepiness was linked to lower odds of prevalent (OR=0.44; p=0.010) and incident hypertension (OR=0.31; p=0.043).
  • Combining objective sleepiness with EDS nullified the protective effect against hypertension.

Cite This Study

Athanasiou et al. (2025) studied this question.

synapsesocial.com/papers/69401b262d562116f28f784fhttps://doi.org/10.1093/sleep/zsaf394
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  1. 10985 Excessive Daytime Sleepiness and Prevalent and Incident Hypertension: The Modifying Effect of Objective Sleep Disturbance2026
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  3. 3Objective sleep characteristics and hypertension: a community-based cohort study2024 · 2 citations
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  5. 51101 Association of Depression and Subjective-Objective Discrepancy in Excessive Daytime Sleepiness2026