Randomized trial examines hypertension risks in individuals with excessive daytime sleepiness and sleep disturbances, suggesting important clinical implications.
Key Points
This study investigates how excessive daytime sleepiness (EDS) affects the risk of hypertension and whether this relationship is modified by sleep disturbance markers.
Examined 1741 adults from the Penn State Adult Cohort for prevalent hypertension and followed 786 subjects for incident hypertension over 7.5 years.
Utilized polysomnography to assess sleep-onset latency and classify individuals based on EDS status and sleep disturbance.
Applied logistic regression to adjust for various covariates including age, BMI, and substance use.
EDS linked to significantly higher odds of prevalent hypertension (OR:1.52; 95%CI:1.01-2.27; p=0.044) and incident hypertension (OR:1.74; 95%CI:1.05-2.87; p=0.030).
Combination of EDS with prolonged sleep-onset latency increased odds of prevalent hypertension (OR:2.34; 95%CI:1.18-4.63; p=0.015).
EDS coupled with prolonged sleep-onset latency significantly raised odds of incident hypertension (OR:3.43; 95%CI:1.58-7.41; p=0.002).